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Ingredients:
Resveratrol Extract [Tiger cane] ... 16 mg.
(from 200 mg. Polygonum cuspidatum 8% total resveratrols)
Grapeskin Extract (Ancellota lambrusco) ... 100 mg.
(30% polyphenols)
Grapeseed Extract (Vitis vinifera) ... 50 mg.
(95% polyphenols)
Green Tea 5:1 Extract (Camellia sinensis) ... 200 mg.
(45% polyphenolics)
Vitamin C (as ascorbic acid) ... 100 mg.
Other Ingredients: Cellulose, stearic acid, modified cellulose gum, magnesium stearate and silicon dioxide.
Suggested Usage: Take 1 to 2 tablets per day with food or juice, or as directed by your qualified health consultant.
Description: * Resveratrol Synergy
Cardiovascular Protection and Capillary Strength
Supplies a Synergistic Blend of Potent Natural Antioxidants and Free Radical Scavengers.
Protects Circulation and Heart Function by Inhibiting Platelet Aggregation and Reducing LDL Oxidation.
Contains the Biologically Active Flavonoid Resveratrol, Plus Catechins, Anthocyanins and Proanthocyanins.
Inhibits the Premature Oxidation of Vitamin C and Spares the Vitamin for Its Roles in Promoting Capillary Health.
Provides 167% of the Daily Value of Vitamin C in Each Tablet.
Combines the Active Compounds of Green Tea, Grape Skin and Grape Seed.
Resveratrol - Another Secret of Red Wine!
Although small amounts of ethanol from any source is known to increase high-density lipoprotein (HDL) levels, the preponderance of the heart-protective effect of wine comes from the pigments found in the skin of dark grapes. Red wine, depending upon processing, tends to be particularly rich in such pigments, which are liberated during fermentation. One of the most important of these compounds liberated from the grape skins is resveratrol (3,4,5-trihydroxystilbene), which is mentioned routinely in the scientific literature. It originally was researched by the Japanese as a weight-loss product which clears fats from the liver. The compound is formed in the leaves and the skins of grapes to combat disease, especially fungal attack. Treatment with fungicides dramatically reduces resveratrol production by the grape itself, and treatment of wines to reduce the astringent tannin content, as is done with much commercially-produced wine at large vintners, also eliminates most of the protective effect.
Populations that regularly consume red wine are noted for longevity and general good health. This health-promoting effect is sometimes referred to as the ""French Paradox"" because the French consume large amounts of saturated fats and yet exhibit low rates of heart disease. In fact, red wine consumption and superior health is true of much of Mediterranean Europe. Along with resveratrol, red wine also contains catechins, anthocyanins (from the skin) and proanthocyanins (from the grape seeds). Therefore, synergy found in Jarrow Formulas Resveratrol Synergy is a natural one.
Jarrow Formulas has used especially rich sources of resveratrol, catechins, anthocyanins and proanthocyanins to create a concentrated supplement designed to provide the cardiovascular and capillary protection found with red wine. Resveratrol is extracted from Huzhang (Polygonum cuspidatum, "tiger cane") root, catechins are derived from green tea extract, anthocyanins from grape skin extract, and proanthocyanins from grape seed extract. To these are added vitamin C, the compound used by the body to support the production of collagen and the structures made from it. All these compounds are powerful antioxidants and free radical scavengers, too.
Phytoestrogens Shine
Phytoestrogens exhibit numerous physiological effects. For instance, resveratrol significantly enhances endothelium-dependent vascular relaxation in response to acetylcholine in some animal models. Similarly, this phenolic compound influence bone strength in these models.
Just as interesting is the inhibitory impact of resveratrol upon a number of environmental toxins. Aryl hydrocarbon receptor ligands are environmental contaminants found at high levels in cigarette smoke. They also are present in many other sources of air pollution. The prototypical compound is known as dioxin. There is an increasing body of knowledge which links cigarette smoke to osteoporosis and to periodontal disease, although the direct effects of smoke-associated aryl hydrocarbons on bone are not well understood. Resveratrol is a pure antagonist to aryl hydrocarbons and this suggests that the compound may prove to be protective against certain classes of toxins that are now common in the environment.
Cardiovascular Protection
As noted already, population studies suggest that the consumption of wine, particularly of red wine, promotes cardiovascular health. The cardioprotective effect is normally attributed to antioxidants present in the polyphenolic fraction of red wine. Grapes contain a variety of antioxidants, including resveratrol, catechins, anthocyanins and proanthocyanins. Investigations have shown that all of these red wine polyphenolic antioxidants play roles in cardioprotection.
A great deal of research has gone into finding the mechanisms by which polyphenolic compounds protect the cardiovascular system. In part, such protection may be attributed to their ability to directly scavenge peroxyl and hydroxyl radicals and reduce oxidative stress. These actions, among other things, protect low-density lipoprotein (LDL) cholesterol from damage. It should be emphasized that these compounds work by different mechanisms and therefore, arguably work best in combination. In published research, resveratrol was more effective than flavonoids as a chelator of copper ions ‘generators of free radicals’ and less effective as a free-radical scavenger than some of the other grape components. Besides the inhibition of LDL oxidation, exposure to wine/resveratrol appears to modulate vascular cell functions and suppress excessive platelet aggregation.
Very recent research into cardiovascular health has suggested still other culprits: inflammation, perhaps from bacterial attack. Surprisingly, anthocyanins and proanthocyanins also can act as antibacterial and antiviral agents. For instance, these tannins somehow coat viruses and prevent them from entering cells.
A Synergistic Supporting Cast
One of the primary benefits of resveratrol and of proanthocyanins is the protection of vitamin C against premature oxidation, especially by copper and other metal ions found in the blood and tissues. Therefore, it makes good sense to include vitamin C along with its protectors. Broader protection comes from the inclusion of a concentrated green tea extract for its variety of catechins, grape skin extract for anthocyanins and grape seed extract for OPC (oligomeric proanthocyanidins, 95% polyphenols). This means that five of the world‚s best researched antioxidants can now be found together in Reveratrol Synergy.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
